PLD3 antibody (N-Term)

Catalog No. ABIN5517655

The Rabbit Polyclonal anti-PLD3 antibody has been validated for WB. It is suitable to detect PLD3 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for PLD3 antibody (N-Term) (ABIN5517655)

Target: PLD3 (Phospholipase D family member 3 (PLD3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLD3 Antibody

Binding Specificity: N-Term

Sequence: PNASTGNPST SQAWLGLLAG AHSSLDIASF YWTLTNNDTH TQEPSAQQGE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PLD3. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PLD3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLD3

Target: PLD3 (Phospholipase D family member 3 (PLD3))

Alternative Name: PLD3

Background: This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alias Symbols: PLD3,

Protein Interaction Partner: UBC, EGFR, SUMO1, NEDD8, NUDCD1, ERP44, FUBP1, PPP5C, EIF2S3, NFKB1, FBXO6, SPP1, TK1, BCL2L1, ANXA7, HGS,

Protein Size: 490

Gene ID: 23646

NCBI Accession: XP_006723187

UniProt: Q8IV08

Pathways: SARS-CoV-2 Protein Interactome