PLD3 antibody (N-Term)

Catalog No. ABIN5517655

Product Details anti-PLD3 Antibody

Target: PLD3 (Phospholipase D family member 3 (PLD3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLD3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PNASTGNPST SQAWLGLLAG AHSSLDIASF YWTLTNNDTH TQEPSAQQGE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PLD3. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PLD3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLD3

Target: PLD3 (Phospholipase D family member 3 (PLD3))

Alternative Name: PLD3 (PLD3 Products)

Background: This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alias Symbols: PLD3,

Protein Interaction Partner: UBC, EGFR, SUMO1, NEDD8, NUDCD1, ERP44, FUBP1, PPP5C, EIF2S3, NFKB1, FBXO6, SPP1, TK1, BCL2L1, ANXA7, HGS,

Protein Size: 490

Gene ID: 23646

NCBI Accession: XP_006723187

UniProt: Q8IV08

Pathways: SARS-CoV-2 Protein Interactome