TSSC4 antibody (N-Term)

Catalog No. ABIN5517719

The Rabbit Polyclonal anti-TSSC4 antibody (ABIN5517719) specifically detects TSSC4 in WB. The antibody is reactive with Human, Mouse, Rat and Cow samples.

Quick Overview for TSSC4 antibody (N-Term) (ABIN5517719)

Target: TSSC4 (Tumor Suppressing Subtransferable Candidate 4 (TSSC4))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSSC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TSSC4 Antibody

Binding Specificity: N-Term

Purpose: TSSC4 Antibody - N-terminal region

Sequence: DLSLPGGAEV EALSPMGLPG EEDSGPDEPP SPPSGLLPAT VQPFHLRGMS

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 77%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against TSSC4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TSSC4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52088-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSSC4

Target: TSSC4 (Tumor Suppressing Subtransferable Candidate 4 (TSSC4))

Alternative Name: TSSC4

Background:

Background Information: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes, however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene.

Gene Name: tumor suppressing subtransferable candidate 4

Protein Name: protein TSSC4

Molecular Weight: 36kDa

Gene ID: 10078

UniProt: Q9Y5U2