TSSC4 antibody

Catalog No. ABIN7231950

This Rabbit Polyclonal antibody specifically detects TSSC4 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TSSC4 antibody (ABIN7231950)

Target: TSSC4 (Tumor Suppressing Subtransferable Candidate 4 (TSSC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSSC4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TSSC4 Antibody

Purpose: Rabbit Anti-TSSC4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TSSC4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TSSC4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TSSC4

Target: TSSC4 (Tumor Suppressing Subtransferable Candidate 4 (TSSC4))

Alternative Name: TSSC4

Background: Protein TSSC4, Tumor-suppressing STF cDNA 4 protein, Tumor-suppressing subchromosomal transferable fragment candidate gene 4 proteinTSSC4 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes, however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. TSSC4 (Tumor Suppressing Subtransferable Candidate 4) is a Protein Coding gene. Diseases associated with TSSC4 include Beckwith-Wiedemann Syndrome and Wilson-Turner Syndrome.

Molecular Weight: 36kD

Gene ID: 10078

UniProt: Q9Y5U2