RECK antibody (Middle Region)
Quick Overview for RECK antibody (Middle Region) (ABIN5517762)
Target
See all RECK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Purpose
- RECK Antibody - middle region
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Sequence
- GSIICKSDCV EILKKCGDQN KFPEDHTAES ICELLSPTDD LKNCIPLDTY
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against RECK. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human RECK
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59229-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- prevent freeze-thaw cycles
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Storage
- 4 °C,-20 °C
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Storage Comment
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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Alternative Name
- RECK
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Background
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Background Information: The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.
Gene Name: reversion-inducing-cysteine-rich protein with kazal motifs
Alternative Symbols: ST15
Protein Name: Reversion-inducing cysteine-rich protein with Kazal motifs
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Molecular Weight
- 106kDa
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Gene ID
- 8434
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NCBI Accession
- NP_066934
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UniProt
- O95980
Target
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