GMDS antibody (N-Term)

Catalog No. ABIN5517890

The Rabbit Polyclonal anti-GMDS antibody (ABIN5517890) specifically detects GMDS in WB. The antibody is reactive with Human samples.

Quick Overview for GMDS antibody (N-Term) (ABIN5517890)

Target: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMDS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GMDS Antibody

Binding Specificity: N-Term

Sequence: HAPARCPSAR GSGDGEMGKP RNVALITGIT GQDGSYLAEF LLEKGYEVHG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GMDS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GMDS

Target: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Alternative Name: GMDS

Background: GDP-mannose 4,6-dehydratas catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans.

Alias Symbols: GMD, SDR3E1

Protein Size: 372

Gene ID: 2762

NCBI Accession: NM_001253846, NP_001240775

UniProt: O60547