CD3G antibody (C-Term)

Catalog No. ABIN5518078

Product Details anti-CD3G Antibody

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD3G antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ELNAATISGF LFAEIVSIFV LAVGVYFIAG QDGVRQSRAS DKQTLLPNDQ

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against CD3G. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD3G

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD3G

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Alternative Name: CD3G (CD3G Products)

Synonyms: Ctg-3 antibody, Ctg3 antibody, T3g antibody, CD3-GAMMA antibody, T3G antibody, CD3 antigen, gamma polypeptide antibody, CD3g molecule antibody, Cd3g antibody, CD3G antibody

Background: The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Alias Symbols: T3G

Protein Interaction Partner: UBC, NR3C1, FYN, CD3E, CD3D,

Protein Size: 182

Gene ID: 917

NCBI Accession: XP_006719004

UniProt: P09693

Pathways: TCR Signaling, CXCR4-mediated Signaling Events