MC3R antibody (N-Term)

Catalog No. ABIN5518775

The Rabbit Polyclonal anti-MC3R antibody (ABIN5518775) specifically detects MC3R in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MC3R antibody (N-Term) (ABIN5518775)

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC3R antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MC3R Antibody

Binding Specificity: N-Term

Purpose: Anti-MC3 Receptor/MC3R Antibody

Sequence: NALETIMIAI VHSDYLTFED QFIQHMDNIF D

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by six amino acids,and from the related rat sequence by seven amino acids.

Characteristics: Anti-MC3 Receptor/MC3R Antibody. Tested in WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MC3 Receptor, different from the related mouse sequence by six amino acids, and from the related rat sequence by seven amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MC3R

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Alternative Name: MC3R

Background:

Background: Melanocortin receptor 3 is a protein that in humans is encoded by the MC3R gene. It is mapped to 20q13.2. This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.

Gene Full Name: melanocortin 3 receptor

Molecular Weight: 42 kDa

UniProt: P41968

Pathways: cAMP Metabolic Process