Ancient Ubiquitous Protein 1 antibody (C-Term)

Catalog No. ABIN5530367

This Rabbit Polyclonal antibody specifically detects Ancient Ubiquitous Protein 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Ancient Ubiquitous Protein 1 antibody (C-Term) (ABIN5530367)

Target: Ancient Ubiquitous Protein 1 (Aup1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ancient Ubiquitous Protein 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Ancient Ubiquitous Protein 1 Antibody

Binding Specificity: AA 440-468, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AUP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the C-terminal region of human AUP1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Ancient Ubiquitous Protein 1

Target: Ancient Ubiquitous Protein 1 (Aup1)

Alternative Name: AUP1

Background: This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.

Molecular Weight: 53 kDa

Gene ID: 550

UniProt: Q9Y679