PCGF2 antibody (AA 121-150)

Catalog No. ABIN5531018

This Rabbit Polyclonal antibody specifically detects PCGF2 in WB. It exhibits reactivity toward Human.

Quick Overview for PCGF2 antibody (AA 121-150) (ABIN5531018)

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCGF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCGF2 Antibody

Binding Specificity: AA 121-150

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PCGF2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.49 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PCGF2

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Alternative Name: PCGF2

Background: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Molecular Weight: 38 kDa

Gene ID: 7703

UniProt: P35227

Pathways: Chromatin Binding