MXI1 antibody (AA 53-82)

Catalog No. ABIN5531570

This Rabbit Polyclonal antibody specifically detects MXI1 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for MXI1 antibody (AA 53-82) (ABIN5531570)

Target: MXI1 (MAX Interactor 1 (MXI1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MXI1 Antibody

Binding Specificity: AA 53-82

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MXI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Alternative Name: MXI1

Background: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Molecular Weight: 26 kDa

Gene ID: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location