RING1 antibody (N-Term)

Catalog No. ABIN5532032

This Rabbit Polyclonal antibody specifically detects RING1 in WB. It exhibits reactivity toward Human.

Quick Overview for RING1 antibody (N-Term) (ABIN5532032)

Target: RING1 (Ring Finger Protein 1 (RING1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RING1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RING1 Antibody

Binding Specificity: AA 95-123, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RING1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the N-terminal region of human RING1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for RING1

Target: RING1 (Ring Finger Protein 1 (RING1))

Alternative Name: RING1

Background: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Molecular Weight: 42 kDa

Gene ID: 6015

UniProt: Q06587