SNX15 antibody (C-Term)
Quick Overview for SNX15 antibody (C-Term) (ABIN5532125)
Target
See all SNX15 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 223-251, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This SNX15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the C-terminal region of human SNX15.
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Isotype
- Ig Fraction
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Application Notes
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SNX15 (Sorting Nexin 15 (SNX15))
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Alternative Name
- SNX15
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Background
- This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms. [provided by RefSeq].
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Molecular Weight
- 38 kDa
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Gene ID
- 29907
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UniProt
- Q9NRS6
Target
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