MED17 antibody (AA 332-361)

Catalog No. ABIN5533371

The Rabbit Polyclonal anti-MED17 antibody has been validated for WB. It is suitable to detect MED17 in samples from Human.

Quick Overview for MED17 antibody (AA 332-361) (ABIN5533371)

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MED17 Antibody

Binding Specificity: AA 332-361

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MED17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 amino acids from the Central region of human MED17.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Alternative Name: MED17

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Molecular Weight: 73 kDa

Gene ID: 9440

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha