CHD1L antibody (AA 561-590)
Quick Overview for CHD1L antibody (AA 561-590) (ABIN5533947)
Target
See all CHD1L AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 561-590
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This CHD1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-590 amino acids from the Central region of human CHD1L.
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Isotype
- Ig Fraction
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Application Notes
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.4 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))
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Alternative Name
- CHD1L
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Background
- In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM].
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Molecular Weight
- 101 kDa
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Gene ID
- 9557
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UniProt
- Q86WJ1
Target
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