NFS1 antibody (AA 121-149)

Catalog No. ABIN5534094

The Rabbit Polyclonal anti-NFS1 antibody is suitable to detect NFS1 in samples from Human. It has been validated for WB.

Quick Overview for NFS1 antibody (AA 121-149) (ABIN5534094)

Target: NFS1 (NFS1, Cysteine Desulfurase (NFS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NFS1 Antibody

Binding Specificity: AA 121-149

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NFS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human NFS1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NFS1

Target: NFS1 (NFS1, Cysteine Desulfurase (NFS1))

Alternative Name: NFS1

Background: Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH . The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.

Molecular Weight: 50 kDa

Gene ID: 9054

UniProt: Q9Y697

Pathways: Transition Metal Ion Homeostasis