LIG3 antibody (C-Term)

Catalog No. ABIN5534167

The Rabbit Polyclonal anti-LIG3 antibody (ABIN5534167) specifically detects LIG3 in WB. The antibody is reactive with Human samples.

Quick Overview for LIG3 antibody (C-Term) (ABIN5534167)

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIG3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LIG3 Antibody

Binding Specificity: AA 793-822, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LIG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 793-822 amino acids from the C-terminal region of human LIG3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Alternative Name: LIG3

Background: This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 113 kDa

Gene ID: 3980

UniProt: P49916

Pathways: DNA Damage Repair