CD70 antibody (AA 72-101)

Catalog No. ABIN5535986

This Rabbit Polyclonal antibody specifically detects CD70 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD70 antibody (AA 72-101) (ABIN5535986)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD70 Antibody

Binding Specificity: AA 72-101

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Molecular Weight: 21 kDa

Gene ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints