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CD70 antibody (AA 72-101)

CD70 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5535986
  • Target See all CD70 Antibodies
    CD70 (CD70 Molecule (CD70))
    Binding Specificity
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 72-101
    Reactivity
    • 92
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 61
    • 30
    • 7
    • 2
    • 1
    Rabbit
    Clonality
    • 62
    • 38
    • 1
    Polyclonal
    Conjugate
    • 49
    • 13
    • 9
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD70 antibody is un-conjugated
    Application
    • 51
    • 44
    • 43
    • 36
    • 25
    • 19
    • 18
    • 11
    • 11
    • 9
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CD70 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CD70 (CD70 Molecule (CD70))
    Alternative Name
    CD70 (CD70 Products)
    Synonyms
    CD27LG antibody, Cd27l antibody, Tnfsf7 antibody, CD27L antibody, TNFSF7 antibody, CD70 antigen antibody, CD70 molecule antibody, Cd70 molecule antibody, Cd70 antibody, CD70 antibody
    Background
    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
    Molecular Weight
    21 kDa
    Gene ID
    970
    UniProt
    P32970
    Pathways
    Cancer Immune Checkpoints
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