FOLR2 antibody (N-Term)

Catalog No. ABIN5536409

This Rabbit Polyclonal antibody specifically detects FOLR2 in WB. It exhibits reactivity toward Human.

Quick Overview for FOLR2 antibody (N-Term) (ABIN5536409)

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOLR2 Antibody

Binding Specificity: AA 17-44, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human FOLR2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Alternative Name: FOLR2

Background: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

Molecular Weight: 29 kDa

Gene ID: 2350

UniProt: P14207

Pathways: Dicarboxylic Acid Transport