GLRB antibody (N-Term)

Catalog No. ABIN5536519

This anti-GLRB antibody is a Rabbit Polyclonal antibody detecting GLRB in WB. Suitable for Human.

Quick Overview for GLRB antibody (N-Term) (ABIN5536519)

Target: GLRB (Glycine Receptor, beta (GLRB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLRB Antibody

Binding Specificity: AA 103-132, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GLRB

Target: GLRB (Glycine Receptor, beta (GLRB))

Alternative Name: GLRB

Background: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Molecular Weight: 56 kDa

Gene ID: 2743

UniProt: P48167