PLK2 antibody (C-Term)

Catalog No. ABIN5537875

This anti-PLK2 antibody is a Rabbit Polyclonal antibody detecting PLK2 in WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for PLK2 antibody (C-Term) (ABIN5537875)

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PLK2 Antibody

Binding Specificity: AA 375-406, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PLK2 (SNK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-406 amino acids from the C-terminal region of human PLK2 (SNK).

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PLK2

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Alternative Name: PLK2

Background: Plks (polo-like kinases) encode serine/threonine kinases that are closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo-like kinases, which include Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk (for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cell proliferation. Plk protein accumulates in the cell during S and G2 phases of the cell cycle, and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk are immediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.

Molecular Weight: 78 kDa

Gene ID: 10769

UniProt: Q9NYY3