PUS10 antibody (N-Term)

Catalog No. ABIN5537983

The Rabbit Polyclonal anti-PUS10 antibody (ABIN5537983) specifically detects PUS10 in WB. The antibody is reactive with Human samples.

Quick Overview for PUS10 antibody (N-Term) (ABIN5537983)

Target: PUS10 (Pseudouridylate Synthase 10 (PUS10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PUS10 Antibody

Binding Specificity: AA 52-78, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PUS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human PUS10.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PUS10

Target: PUS10 (Pseudouridylate Synthase 10 (PUS10))

Alternative Name: PUS10

Background: Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM].

Molecular Weight: 60 kDa

Gene ID: 150962

UniProt: Q3MIT2