DIAPH3 antibody (C-Term)

Catalog No. ABIN5539348

Product Details anti-DIAPH3 Antibody

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Binding Specificity: AA 1061-1090, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIAPH3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DIAPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for DIAPH3

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Alternative Name: DIAPH3 (DIAPH3 Products)

Synonyms: Diap3 antibody, DIAP3 antibody, DIAPH3 antibody, 4930417P13Rik antibody, Dia2 antibody, Diaph3 antibody, Drf3 antibody, mDia2 antibody, mKIAA4117 antibody, p134MDia2 antibody, AN antibody, AUNA1 antibody, DIA2 antibody, DRF3 antibody, NSDAN antibody, diap3 antibody, diaphanous-related formin 3 antibody, diaphanous related formin 3 antibody, diaphanous homolog 3 (Drosophila) antibody, Diaph3 antibody, DIAPH3 antibody

Background: DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).

Molecular Weight: 137 kDa

Gene ID: 81624

UniProt: Q9NSV4