SOCS1 antibody (C-Term) (Biotin)

Catalog No. ABIN5539590

The Goat Polyclonal anti-SOCS1 antibody has been validated for WB and ELISA. It is suitable to detect SOCS1 in samples from Human and Mouse.

Quick Overview for SOCS1 antibody (C-Term) (Biotin) (ABIN5539590)

Target: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This SOCS1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-SOCS1 Antibody (Biotin)

Binding Specificity: C-Term

Purpose: SOCS1, biotinylated

Sequence: VLRDYLSSFP FQI.

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 24 kDa band observed in Mouse Spleen lysates (calculated MW of 23.7 kDa according to Mouse NP_034026.1). See non-biotinylated parental product's datasheet for further QC data. Recommended concentration: 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for SOCS1

Target: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Alternative Name: SOCS1

Background: SOCS1, suppressor of cytokine signaling 1, CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3, JAK binding protein, JAK-binding protein, STAT induced SH3 protein 1, STAT-induced STAT inhibitor 1, TIP-3, Tec-interacting protein 3, cytokine-inducible SH2 protein 1

Gene ID: 8651, 12703

NCBI Accession: NP_003736

Pathways: JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling, Response to Growth Hormone Stimulus