TEK antibody (PE)

Catalog No. ABIN5540122

This anti-TEK antibody is a Mouse Monoclonal antibody detecting TEK in FACS. Suitable for Human.

Quick Overview for TEK antibody (PE) (ABIN5540122)

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TEK antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: Cl-16

Product Details anti-TEK Antibody (PE)

Specificity: The unconjugated monoclonal antibody will detect native human TIE-2 /TEK in ELISA experiments and on the surface of different human cell types. Species: Human.

Purification: Protein G Chromatography

Immunogen: Recombinant human soluble CD202b / TIE-2 protein

Isotype: IgG1

Application Details

Application Notes: FACS analysis and cell sorting: ≤ 0.5 μg/mL in 100 μL.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for TEK

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Alternative Name: cd202b,tek

Background: TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.

UniProt: Q02763

Pathways: RTK Signaling, Growth Factor Binding