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NGFR antibody (AA 1-160) (Biotin)

This Mouse Monoclonal antibody specifically detects NGFR in FACS. It exhibits reactivity toward Human, Rabbit, Cat, Ferret and Primate.
Catalog No. ABIN5540156

Quick Overview for NGFR antibody (AA 1-160) (Biotin) (ABIN5540156)

Target

See all NGFR Antibodies
NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivity

  • 201
  • 63
  • 54
  • 39
  • 29
  • 27
  • 26
  • 22
  • 12
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Rabbit, Cat, Ferret, Primate

Host

  • 110
  • 98
  • 4
  • 1
Mouse

Clonality

  • 137
  • 76
Monoclonal

Conjugate

  • 97
  • 17
  • 11
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NGFR antibody is conjugated to Biotin

Application

  • 115
  • 92
  • 83
  • 58
  • 43
  • 43
  • 28
  • 27
  • 20
  • 16
  • 15
  • 15
  • 12
  • 7
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

NGFR5
  • Binding Specificity

    • 38
    • 16
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-160

    Specificity

    This antibody recognizes CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within ammino acids 1 - 160.

    Immunogen

    Purified CD271 protein isolated from human melanoma cell line A875

    Isotype

    IgG1
  • Application Notes

    Indirect immunofluorescence analysis by Flow cytometry: 1:200 as starting point.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

    Expiry Date

    12 months
  • Target

    NGFR (Nerve Growth Factor Receptor (NGFR))

    Alternative Name

    cd271,ngfr

    Background

    CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

    UniProt

    P08138

    Pathways

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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