CD44 antibody (PE)

Catalog No. ABIN5540180

This Mouse Monoclonal antibody specifically detects CD44 in FACS. It exhibits reactivity toward Horse. It has been mentioned in 3+ publications

Quick Overview for CD44 antibody (PE) (ABIN5540180)

Target: CD44

Reactivity: Horse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: CVS18

Product Details anti-CD44 Antibody (PE)

Specificity: Clone CVS18 antibody detects equine CD44 and may be used as a pan equine leucocyte marker. Species: Equine (Horse).

Purification: Affinity chromatography on Protein G

Immunogen: Equine leucocytes

Isotype: IgG1

Application Details

Application Notes: Flow cytometry : Neat, use 10 μL to label 10 6 cells in 100 μL.

Restrictions: For Research Use only

Handling

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Expiry Date: 12 months

References for anti-CD44 antibody (PE) (ABIN5540180)

Carrade, Lame, Kent, Clark, Walker, Borjesson: "Comparative Analysis of the Immunomodulatory Properties of Equine Adult-Derived Mesenchymal Stem Cells()." in: Cell medicine, Vol. 4, Issue 1, pp. 1-11, (2012) (PubMed).

Radcliffe, Flaminio, Fortier: "Temporal analysis of equine bone marrow aspirate during establishment of putative mesenchymal progenitor cell populations." in: Stem cells and development, Vol. 19, Issue 2, pp. 269-82, (2010) (PubMed).

Schneider, Essmann, Kletke, Rio, Hanenberg, Wetzel, Schulze-Osthoff, Nürnberg, Piekorz: "The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival." in: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29273-83, (2007) (PubMed).

Target Details for CD44

Target: CD44

Alternative Name: cd44

Background: CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.

UniProt: Q05078

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling