DNAL1 antibody (AA 1-190)

Catalog No. ABIN5540311

The Mouse Monoclonal anti-DNAL1 antibody (Clone AT29E4) (ABIN5540311) specifically detects DNAL1 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for DNAL1 antibody (AA 1-190) (ABIN5540311)

Target: DNAL1 (Dynein, Axonemal, Light Chain 1 (DNAL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DNAL1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT29E4

Product Details anti-DNAL1 Antibody

Binding Specificity: AA 1-190

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human DNAL1 (1-190aa) purified from E. coli

Isotype: IgG2b

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for DNAL1

Target: DNAL1 (Dynein, Axonemal, Light Chain 1 (DNAL1))

Alternative Name: dnal1

Background: DNAL1, also known as dynein light chain 1 axonemal, is component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. DNAL1 is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Homozygous mutations in the DNAL1 gene are associated with primary ciliary dyskinesia 16 (CILD16) which is a disorder characterized by abnormalities of motile cilia.

UniProt: Q4LDG9