NMUR2 antibody

Catalog No. ABIN5540518

The Mouse Monoclonal anti-NMUR2 antibody (Clone 2A2) (ABIN5540518) specifically detects NMUR2 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for NMUR2 antibody (ABIN5540518)

Target: NMUR2 (Neuromedin U Receptor 2 (NMUR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NMUR2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2A2

Product Details anti-NMUR2 Antibody

Specificity: This antibody detects NMU-R2. The specificity of the antibody was verified by flow cytometry with cells expressing the recombinant protein.

Purification: Protein G

Immunogen: DNA vaccine

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on paraffin sections: 20 μg/mL (1/20). Positive control: Sceletal muscle.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for NMUR2

Target: NMUR2 (Neuromedin U Receptor 2 (NMUR2))

Alternative Name: nmur2

Background: Neuromedin - U receptor 2 (NMU - R2) belongs to the G - protein coupled receptor 1 family. The mature protein is made up of 4 15 amino acids with one disulfide bond and three N - linked glycosylation sites. NMU - R2 is the receptor for Neuromedin s U (NMU) and S (NMS) which regulate important physiological functions, including feeding, energy balance, stress response, and nociception in the central nervous system (CNS). NMU - R2 is predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. Strong expression has also been described in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, spleen and thymus.

UniProt: Q9GZQ4

Pathways: Feeding Behaviour