MANF antibody

Catalog No. ABIN5540962

The Mouse Monoclonal anti-MANF antibody (Clone 1G12) (ABIN5540962) specifically detects MANF in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for MANF antibody (ABIN5540962)

Target: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MANF antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 1G12

Product Details anti-MANF Antibody

Specificity: Recognizes Human MANF. Other species not tested.

Purification: Affinity Chromatography on Protein G

Immunogen: Recombinant Human MANF produced using CHO-based. Antigen is purified from cell culture supernatant.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/32000. Western Blot: 1/2000-1/4000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.4 Preservatives: 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for MANF

Target: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Alternative Name: armet,arp

Background: MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson's disease (Lindholm et al., 2008, Voutilainen et al., 2009). When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.

UniProt: P55145