CRISP3 antibody

Catalog No. ABIN5541466

The Mouse Monoclonal anti-CRISP3 antibody (Clone LV-2A2) (ABIN5541466) specifically detects CRISP3 in FACS, EIA and ELISA (Detection). The antibody is reactive with Human samples.

Quick Overview for CRISP3 antibody (ABIN5541466)

Target: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRISP3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Enzyme Immunoassay (EIA), ELISA (Detection)

Clone: LV-2A2

Product Details anti-CRISP3 Antibody

Specificity: Recognizes Cysteine-Rich Secretory Protein 3 (CRISP3).

Purification: Protein G Affinity Chromatography.

Immunogen: Genetic immunisation with cDNA encoding Human CRISP3.

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 μg/10e6 cells. ELISA (detection): Clone LU-5E11-A7 as capture antibody. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Storage: 4 °C,-20 °C

Storage Comment: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CRISP3

Target: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Alternative Name: crisp3

Background: Cysteine-rich secretory protein 3 (CRISP3) belongs to the cysteine-rich secretory protein family. CRISPs are characterized by a cysteine-rich domain at the COOH terminal that form 8 intramolecular disulfide bonds (1). Mammalian members of the CRISP family are expressed predominantly in the male reproductive tract and are implicated in the process of reproduction from spermiogenesis, posttesticular sperm maturation and capacitation to oocyte-sperm fusion (2). CRISP3 is epithelium-specific and found predominantly in salivary gland, pancreas and prostate, and in less abundance in the epididymis, ovary, thymus and colon. CRISP3 is up-regulated in malignant prostatic epithelium, therefore, it can be used as a potential prostate cancer biomarker (3).

UniProt: P54108