GLP1R antibody

Catalog No. ABIN5541471

The Mouse Monoclonal anti-GLP1R antibody has been validated for IHC (p). It is suitable to detect GLP1R in samples from Human.

Quick Overview for GLP1R antibody (ABIN5541471)

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLP1R antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1H4

Product Details anti-GLP1R Antibody

Specificity: This antibody detects GLP-1R. The specificity of the antibody was verified by flow cytometry with cells expressing the recombinant protein. Aff. Const.: Human

Purification: Protein G

Immunogen: DNA vaccine

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on paraffin sections: 2 μg/mL (1/100) pretreatment with microwave required. Positive control: pancreas / adrenal.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for GLP1R

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Alternative Name: glp1 receptor

Background: Glucagon - like peptide 1 receptor belongs to the G - protein coupled receptor 2 family. The mature protein is made up of 440 amino acids with four disulfide bonds and three N - linked glycosylation sites. Glucagon - like peptide - 1 (GLP - 1) is a peptide hormone that functions as a messenger between various organs and tissues involved in glucose metabolism, and controls nutrient ingestion. Important sources for GLP - 1 include the intestine and brain stem and hypothalamus, while the receptor (GLP - 1R) is prominently expressed in pancreas, areas of the brain such as the hypothalamus, and peripheral nerves.

UniProt: P43220

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour