Glutathione Reductase antibody (AA 43-522)

Catalog No. ABIN5541475

The Mouse Monoclonal anti-Glutathione Reductase antibody (Clone AT11D10) (ABIN5541475) specifically detects Glutathione Reductase in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for Glutathione Reductase antibody (AA 43-522) (ABIN5541475)

Target: Glutathione Reductase (GSR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glutathione Reductase antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT11D10

Product Details anti-Glutathione Reductase Antibody

Binding Specificity: AA 43-522

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human GSR (43-522aa) purified from E.coli.

Isotype: IgG1

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Glutathione Reductase

Target: Glutathione Reductase (GSR)

Alternative Name: glutathione reductase

Background: Glutathione reductase(GR) also known as glutathione-disulfide reductase(GSR) is an enzyme that in humans is encoded by the GSR gene. Glutathione reductase catalyzes the reduction of glutathione disulfide (GSSG) to the sulfhydryl form glutathione(GSH), which is a critical molecule in resisting oxidative stress and maintaining the reducing environment of the cell. Glutathione reductase functions as dimeric disulfide oxidoreductase and utilizes an FAD prosthetic group and NADPH to reduce one mole of GSSG to two moles of GSH.

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis