CD22 antibody (Heavy Chain)

Catalog No. ABIN5541614

This Mouse Monoclonal antibody specifically detects CD22 in FACS, IF, ICC and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CD22 antibody (Heavy Chain) (ABIN5541614)

Target: CD22 (CD22 Molecule (CD22))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD22 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 3H4

Product Details anti-CD22 Antibody

Binding Specificity: Heavy Chain

Specificity: This antibody recognizes HLA class I heavy chains (CD22). It can be used for CD22+ cell identification, quantification and isolation.

Purification: Purified

Immunogen: Daudi cells, a Burkitt's lymphoma cell line

Isotype: IgG1

Application Details

Application Notes: Flow cytometry. Immunocytochemistry. Immunohistochemistry on Frozen sections. Recommended Dilutions: 1/100-1/200 for Flow Cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD22

Target: CD22 (CD22 Molecule (CD22))

Alternative Name: cd22 (

Background: CD22 is a 140 kDa transmembrane type 1 protein, which is a member of the sialic acid binding immunoglobulin (Ig)-like lectin family of proteins. CD22 is a B-lymphocyte specific protein, which is differentially expressed during B-cell development. It is expressed in the cytoplasm of immature B-cells and on the surface of mature B-cells. The CD22 Molecule functions as an adhesion receptor, binding to alpha 2-6 linked sialic acids on glycoproteins expressed by leucocytes and erythrocytes. The molecule is also involved in the regulation of B-cell antigen receptor signaling.

UniProt: P35329