MMP17 antibody

Catalog No. ABIN5542064

This Mouse Monoclonal antibody specifically detects MMP17 in EIA and Neut. It exhibits reactivity toward Human.

Quick Overview for MMP17 antibody (ABIN5542064)

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMP17 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Neutralization (Neut)

Clone: 12N24

Product Details anti-MMP17 Antibody

Specificity: This antibody recognizes Human MMP-17 by direct ELISA.

Purification: Protein G Chromatography

Immunogen: Recombinant Human MMP-17

Isotype: IgG2

Application Details

Application Notes: ELISA: 1/1000-1/2000. Neutralization.

Restrictions: For Research Use only

Handling

Buffer: Sterile PBS

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for MMP17

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Alternative Name: mmp-17

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage and is known to be expressed in brain, leukocytes, colon, ovary testis and breast cancer as well as in many transformed and non-transformed cell types. The protein exists in two isoforms: a GPI-anchored form and a second secreted form.

UniProt: Q9ULZ9