MFAP4 antibody (AA 22-255)

Catalog No. ABIN5542149

The Mouse Monoclonal anti-MFAP4 antibody is suitable to detect MFAP4 in samples from Human. It has been validated for WB and EIA.

Quick Overview for MFAP4 antibody (AA 22-255) (ABIN5542149)

Target: MFAP4 (Microfibrillar-Associated Protein 4 (MFAP4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MFAP4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT12D11

Product Details anti-MFAP4 Antibody

Binding Specificity: AA 22-255

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human MFAP4 (22-255aa) purified from E. coli

Isotype: IgG1

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for MFAP4

Target: MFAP4 (Microfibrillar-Associated Protein 4 (MFAP4))

Alternative Name: mfap4

Background: Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Also, MFAP4 play an important role in calcium-dependent cell adhesion or intercellular interactions. These structural features of MFAP4 suggest that it is an extracellular matrix protein involved in cell adhesion or intercellular interactions.

UniProt: P55083