Cathepsin D antibody (AA 1-100)

Catalog No. ABIN5542294

The Mouse Monoclonal anti-Cathepsin D antibody (Clone 2H4H5) (ABIN5542294) specifically detects Cathepsin D in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for Cathepsin D antibody (AA 1-100) (ABIN5542294)

Target: Cathepsin D (CTSD)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cathepsin D antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 2H4H5

Product Details anti-Cathepsin D Antibody

Binding Specificity: AA 1-100

Purpose: CTSD Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CTSD (AA: 1-100) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Cathepsin D

Target: Cathepsin D (CTSD)

Alternative Name: CTSD

Background: This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.

Molecular Weight: 44.6 kDa

UniProt: P07339

Pathways: Peptide Hormone Metabolism