Cathepsin D antibody (AA 1-100)
Quick Overview for Cathepsin D antibody (AA 1-100) (ABIN5542294)
Target
See all Cathepsin D (CTSD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-100
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Purpose
- CTSD Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CTSD (AA: 1-100) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Cathepsin D (CTSD)
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Alternative Name
- CTSD
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Background
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This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
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Molecular Weight
- 44.6 kDa
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UniProt
- P07339
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Pathways
- Peptide Hormone Metabolism
Target
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