RAB8A antibody (AA 68-207)

Catalog No. ABIN5542342

This anti-RAB8A antibody is a Mouse Monoclonal antibody detecting RAB8A in ELISA and FACS. Suitable for Human.

Quick Overview for RAB8A antibody (AA 68-207) (ABIN5542342)

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAB8A antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 7G8B11

Product Details anti-RAB8A Antibody

Binding Specificity: AA 68-207

Purpose: Rab8 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human Rab8 (AA: 68-207) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for RAB8A

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Alternative Name: Rab8

Background: The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Molecular Weight: 23.7 kDa

Gene ID: 4218

UniProt: P61006

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome