CBX3 antibody (AA 1-183)

Catalog No. ABIN5542474

The Mouse Monoclonal anti-CBX3 antibody (Clone 6D1C4) (ABIN5542474) specifically detects CBX3 in IHC, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for CBX3 antibody (AA 1-183) (ABIN5542474)

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBX3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 6D1C4

Product Details anti-CBX3 Antibody

Binding Specificity: AA 1-183

Purpose: CBX3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CBX3 (AA: 1-183) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CBX3

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Alternative Name: CBX3

Background: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Molecular Weight: 20.8 kDa

Gene ID: 11335

UniProt: Q13185