MAPK10 antibody (AA 180-329)
Quick Overview for MAPK10 antibody (AA 180-329) (ABIN5542487)
Target
See all MAPK10 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 180-329
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Purpose
- MAPK10 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human MAPK10 (AA: 180-329) expressed in E. Coli.
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Isotype
- IgG2a
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Application Notes
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
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Alternative Name
- MAPK10
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Background
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
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Molecular Weight
- 52.6 kDa
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UniProt
- P53779
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Pathways
- MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
Target
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