LEF1 antibody (AA 33-138)
Quick Overview for LEF1 antibody (AA 33-138) (ABIN5542525)
Target
See all LEF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 33-138
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Purpose
- LEF1 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human LEF1 (AA: 33-138) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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Alternative Name
- LEF1
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Background
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This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 44.2 kDa
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Gene ID
- 51176
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UniProt
- Q9UJU2
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Pathways
- WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
Target
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