MTRF1 antibody (AA 288-437)

Catalog No. ABIN5542689

Product Details anti-MTRF1 Antibody

Target: MTRF1 (Mitochondrial Translational Release Factor 1 (MTRF1))

Binding Specificity: AA 288-437

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MTRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human RF1 (AA: 288-437) expressed in E. coli.

Clone: 4F9H12

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for MTRF1

Target: MTRF1 (Mitochondrial Translational Release Factor 1 (MTRF1))

Alternative Name: RF1 (MTRF1 Products)

Background:

Description: This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.,

Aliases: ERF, ETF1, ERF1, TB3-1, D5S1995, SUP45L1

Molecular Weight: 49 kDa

Gene ID: 2107

HGNC: 2107