HDAC4 antibody

Catalog No. ABIN5557481

The Rabbit Monoclonal anti-HDAC4 antibody (Clone 6B10) (ABIN5557481) specifically detects HDAC4 in WB and IF (cc). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HDAC4 antibody (ABIN5557481)

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HDAC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 6B10

Product Details anti-HDAC4 Antibody

Purification: Purified by Protein A.

Immunogen: Recombinant human HDAC4 protein, around C-terminal 100aa.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Storage: -20 °C

Storage Comment: Store at -20°C

Expiry Date: 12 months

Target Details for HDAC4

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Alternative Name: HDAC4

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Synonyms: HDAC4Ser246, HDAC4S246, p-HDAC4Ser246, p-HDAC4S246, HD 4, HD4, HDAC 4, HDAC A, HDACA, Histone Deacetylase 4, Histone Deacetylase A, KIAA0288, EC 3.5.1.98, HA6116, HDA4_CAEEL, Histone deacetylase 4, CeHDA-7, Histone deacetylase 7.

Gene ID: 9759

UniProt: P56524

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process