Recombinant HDAC8 antibody (N-Term)

Catalog No. ABIN5557483

The Rabbit Monoclonal anti-HDAC8 antibody is suitable to detect HDAC8 in samples from Human. It has been validated for WB, IF, FACS and ICC.

Quick Overview for Recombinant HDAC8 antibody (N-Term) (ABIN5557483)

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HDAC8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-HDAC8 Antibody

Binding Specificity: N-Term

Purpose: HDAC8 Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant human HDAC8 protein, around N-terminal 150aa.

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), Flow-Cyt(1 μg/Test), ICC/IF(1:50-100)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Alternative Name: HDAC8

Background:

Synonyms: HD8, WTS, RPD3, CDA07, CDLS5, MRXS6, HDACL1, Histone deacetylase 8, HDAC8

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

Gene ID: 55869

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process