H2AFZ antibody

Catalog No. ABIN5557486

The Rabbit Monoclonal anti-H2AFZ antibody is suitable to detect H2AFZ in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for H2AFZ antibody (ABIN5557486)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7G8

Product Details anti-H2AFZ Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant human Histone H2A.Z protein, around 1-100aa.

Isotype: IgG

Application Details

Application Notes: IHC-P 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: Histone H2A.Z

Background:

Synonyms: Histone H2A type 1-B/E, HIST1H2AB

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene ID: 3012

UniProt: P04908

Pathways: Telomere Maintenance