Recombinant IRF2 antibody (C-Term)

Catalog No. ABIN5557494

This Rabbit Monoclonal antibody specifically detects IRF2 in WB, IF, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for Recombinant IRF2 antibody (C-Term) (ABIN5557494)

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IRF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IRF2 Antibody

Binding Specificity: C-Term

Purpose: IRF2 Recombinant Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Recombinant human IRF2 protein, around C-terminal 100aa.

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IRF2

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Alternative Name: IRF2

Background:

Synonyms: IRF-2, Interferon regulatory factor 2, IRF2

Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.

Gene ID: 3660

UniProt: P14316