CDK2 antibody

Catalog No. ABIN5557541

This anti-CDK2 antibody is a Rabbit Monoclonal antibody detecting CDK2 in WB and IHC (p). Suitable for Mouse and Rat.

Quick Overview for CDK2 antibody (ABIN5557541)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2E3

Product Details anti-CDK2 Antibody

Purification: Purified by Protein A.

Immunogen: Recombinant human Cdk2 protein, around C-terminal 100aa.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-5000
IHC-P 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Storage: -20 °C

Storage Comment: Store at -20°C

Expiry Date: 12 months

Target Details for CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Alternative Name: Cdk2

Background:

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].

Synonyms: CDKN2, p33(CDK2), Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase, CDK2

Gene ID: 1017

UniProt: P24941

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA