APP antibody (AA 19-305)

Catalog No. ABIN559905

The Mouse Monoclonal anti-APP antibody (Clone 2C12) (ABIN559905) specifically detects APP in WB, ELISA and PLA. The antibody is reactive with Human samples.

Quick Overview for APP antibody (AA 19-305) (ABIN559905)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This APP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Proximity Ligation Assay (PLA)

Clone: 2C12

Product Details anti-APP Antibody

Binding Specificity: AA 19-305

Purpose: Mouse monoclonal antibody raised against a full length recombinant APP.

Sequence: EVPTDGNAGL LAEPQIAMFC GRLNMHMNVQ NGKWDSDPSG TKTCIDTKEG ILQYCQEVYP ELQITNVVEA NQPVTIQNWC KRGRKQCKTH PHFVIPYRCL VGEFVSDALL VPDKCKFLHQ ERMDVCETHL HWHTVAKETC SEKSTNLHDY GMLLPCGIDK FRGVEFVCCP LAEESDNVDS ADAEEDDSDV WWGGADTDYA DGSEDKVVEV AEEEEVAEVE EEEADDDEDD EDGDEVEEEA EEPYEEATER TTSIATTTTT TTESVEEVVR EKWYKEVHSG QARWLML

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: APP (AAH04369.1, 19 a.a. ~ 305 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: APP

Background: Full Gene Name: amyloid beta (A4) precursor protein
Synonyms: AAA,ABETA,ABPP,AD1,APPI,CTFgamma,CVAP,PN2

Gene ID: 351

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour