Calpain S1 antibody (AA 172-260)

Catalog No. ABIN560162

The Mouse Monoclonal anti-Calpain S1 antibody has been validated for WB, ELISA, IF, IHC (p) and RNAi. It is suitable to detect Calpain S1 in samples from Human. There are 3+ publications available.

Quick Overview for Calpain S1 antibody (AA 172-260) (ABIN560162)

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calpain S1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Clone: 3C4

Product Details anti-Calpain S1 Antibody

Binding Specificity: AA 172-260

Purpose: Mouse monoclonal antibody raised against a partial recombinant CAPNS1.

Sequence: KRWQAIYKQF DTDRSGTICS SELPGAFEAA GFHLNEHLYN MIIRRYSDES GNMDFDNFIS CLVRLDAMFR AFKSLDKDGT GQIQVNIQE

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CAPNS1 (AAH00592, 172 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Calpain S1 antibody (ABIN560162)

Iguchi-Hashimoto, Usui, Yoshifuji, Shimizu, Kobayashi, Ito, Murakami, Shiomi, Yukawa, Kawabata, Nojima, Ohmura, Fujii, Mimori: "Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-?B and increased STAT5 signals." in: PLoS ONE, Vol. 6, Issue 10, pp. e27020, (2011) (PubMed).

Tabata, Tabata, Nakano: "The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in mice." in: Clinical and experimental immunology, Vol. 162, Issue 3, pp. 560-7, (2010) (PubMed).

Barker, Leonard, Hansen, Trawick, Ingram, Burdett, Lebold, Walker, Traber: "Vitamin E and C supplementation does not ameliorate muscle dysfunction after anterior cruciate ligament surgery." in: Free radical biology & medicine, Vol. 47, Issue 11, pp. 1611-8, (2009) (PubMed).

Target Details for Calpain S1

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Alternative Name: CAPNS1

Background: Full Gene Name: calpain, small subunit 1
Synonyms: 30K,CALPAIN4,CANP,CANPS,CAPN4,CDPS

Gene ID: 826

Pathways: Apoptosis