Calpain S1 antibody (AA 84-268)

Catalog No. ABIN5775927

This Mouse Monoclonal antibody specifically detects Calpain S1 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for Calpain S1 antibody (AA 84-268) (ABIN5775927)

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calpain S1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1D11

Product Details anti-Calpain S1 Antibody

Binding Specificity: AA 84-268

Purpose: Human CAPNS1 antibody

Purification: Purified

Immunogen: Recombinant human CAPNS1 (84-268aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for Calpain S1

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Alternative Name: CAPNS1

Background: CAPNS1, also known as Calpain small subunit 1, are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Two transcript variants encoding the same protein have been identified for this gene.

NCBI Accession: NP_001740

Pathways: Apoptosis