AKR1C2 antibody (AA 224-323)

Catalog No. ABIN560582

The Mouse Polyclonal anti-AKR1C2 antibody has been validated for WB and ELISA. It is suitable to detect AKR1C2 in samples from Human. There is 1 publication available.

Quick Overview for AKR1C2 antibody (AA 224-323) (ABIN560582)

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This AKR1C2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AKR1C2 Antibody

Binding Specificity: AA 224-323

Purpose: Mouse polyclonal antibody raised against a partial recombinant AKR1C2.

Sequence: EEPWVDPNSP VLLEDPVLCA LAKKHKRTPA LIALRYQLQR GVVVLAKSYN EQRIRQNVQV FEFQLTSEEM KAIDGLNRNV RYLTLDIFAG PPNYPVSDEY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: AKR1C2 (AAH63574, 224 a.a. ~ 323 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-AKR1C2 antibody (ABIN560582)

Su, Liao, Huang, Chu, Lin, Chang: "Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis." in: Toxicology, Vol. 244, Issue 2-3, pp. 257-70, (2008) (PubMed).

Target Details for AKR1C2

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Alternative Name: AKR1C2

Background: Full Gene Name: aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2, bile acid binding protein, 3-alpha hydroxysteroid dehydrogenase, type III)
Synonyms: AKR1C-pseudo,BABP,DD,DD2,DDH2,HAKRD,HBAB,MCDR2

Gene ID: 1646

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process